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Peptides: Superstar Ingredients in Skin Care

For the las two decades, peptides have been acclaimed as one of the most promising age-defying ingredients in skin care products. What messages are the peptides in your skin care delivering to your skin?


Peptides are short amino acid chain sequences, or fragments of protein. They differ from proteins because of their size, with peptides normally comprised of less than 50 amino acids. The smaller the peptide chain, the better its ability to penetrate the deeper layers of the skin.

Varying combinations of amino acids create different types of peptides with different benefits to the skin. Peptides help to address concerns focused on increasing hydration and firmness, smoothing the appearance of fine lines and wrinkles, reducing inflammation, or repairing the skin’s barrier function.

The most commonly used types of peptides in skin care include carrier peptides, enzyme inhibitor peptides, neurotransmitter inhibiting peptides, and signalling peptides.

Carrier peptides transport trace minerals to the skin to boost collagen. Enzyme inhibitor peptides slow down collagen degradation. Neurotransmitter inhibiting peptides work to smooth wrinkles by inhibiting the muscle contractions of expression lines. Signalling peptides send messages to the skin to produce more collagen, elastin, hyaluronic acid, and other proteins.


For bioavailable peptides to have optimal efficacy, they need to be stable and have the ability to effectively penetrate the skin’s barrier. The modification of short peptides with palmitoyl or an acetyl group can significantly increase skin penetration. Innovative skin care products go a step further by incorporating a synergistic blend of peptide combinations with an appropriate delivery system to maximize peptide efficacy.

For example, The Eltraderm Peptide Complex Serum incorporates Acteyl Tetrapeptide-9 and Acetyl Tetrapeptide-11 which target specific proteoglycans and collagen components. Proteoglycans (glycosaminoglycan chains) play an important role in cell-to-cell interaction and the extra cellular matrix (ECM) organization. They have the ability to detect deficiencies and recalibrate cellular functions to encourage the exchange of nutrients and oxygen at the cellular level. With age, proteoglycans decrease and impact the cell regeneration and water regulation in the ECM.

In short, when collagen breaks down with age or damage, peptides send a signal to the skin cells telling them to make more collagen and replenish what’s been lost.

Acetyl Tetrapeptide-9 promotes the production of Collagen I in the dermis and lumican, a specific proteoglycan involved in the synthesis of collagen fibrils and their organization into functional fibers, thereby impacting collagen stabilization.

Acetyl Tetrapeptide-11 targets Collagen XVII in the dermal-epidermal junction and syndecan-1, which is a major component involved in the modulation of epidermal cell proliferation and adhesion, and signalling of growth factors.

Clinical studies and trials on this peptide blend demonstrate a proven increase in collagen density and extracellular organization of collagen fibers, as well as improved epidermal-dermal cohesion, resulting in firmer and plumper skin. They also reveal a visible reduction in the appearance of wrinkles and an increase in skin firming after the first month and continued improvement into the second month of daily usage.

Eltraderm’s Peptide Complex Serum integrates these bioavailable anti-aging tetrapeptides, saccharide complex, and sea fern extract for the ultimate targeted anti-aging serum. This exclusive fusion of active ingredients focuses on visible signs of aging, long-term hydration and moisture-retention, extra supportive care for dry skin, and age spots. Ideal for mature, dehydrated, or dry skin, as well as photo-aging skin. It also helps foster better skin recovery post-procedures.


For years, Matrixyl® 3000 with its benchmark standards and matrikine peptide technology, has been used in skin care products because of its proven anti-aging and anti-wrinkle effects. The key ingredients in Matrixyl® 3000 include Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7.

Palmitoyl Tetrapeptide-1 is deemed a signalling peptide which promotes wrinkle smoothing and improves tone and elasticity. It further strengthens the skin’s underlying supportive elements by stimulating the production of collagen to deliver plumper-looking skin.

Palmitoyl Tetrapeptide-7 inhibits glycation damage to the skin by reducing cell damage during inflammation and promoting glycosaminoglycan renewal. It also stimulates the repair and regeneration of collagen fibers to help improve the skin’s visible elasticity and firmness.

It’s no wonder that these two peptides are revered anti-aging peptides!

The Eltraderm Peptide Cream features a lineup of superior age-defying peptides: Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Acetyl Tetrapeptide-9, and Acetyl Tetrapeptide-11. These four peptides work synergistically to restore the skin’s youthful appearance and strengthen skin’s underlying supportive elements.


Acetyl Tetrapeptide-9 and Acetyl Tetrapeptide-11 - bioavailable, quick efficacy tetrapeptides collaboratively work to rebuild the skin’s appearance with wrinkle reduction and improved skin firmness

Saccharide Complex - relieves dryness and subsequent irritation, as well as strengthens the skin’s barrier with moisture-binding properties

Sea Fern Extract - stimulates the natural process of melanin expression to reduce the appearance of blemishes and brighten the skin’s complexion


Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide 9 - support collagen and glycosaminoglycan renewal, inhibit degradation of the skin matrix, and reinforce the epidermis for a more "plumped" appearance

Acetyl Tetrapeptide-9 and Acetyl Tetrapeptide-11 - deliver anti-wrinkle efficacy with wrinkle depth reduction and improved skin firmness

Time-Released Moisturizing Biopolymers - promote long-lasting hydration with sustained protection to restore the quality of the skin barrier

Hyaluronic Acid - holds moisture and nourishes the stratum corneum, while visibly smoothening and softening the appearance of wrinkles

Preserve the skin’s overall youthful appearance and enhance hydration levels for skin conditions in need of extra moisture and nourishment by adding the Eltraderm Peptide Complex Serum and Peptide Cream to daily skin care rituals.

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